Possible Definitions:
1. Tweak (v. t.) To pinch and pull with a sudden jerk and twist; to twitch; as, to tweak the nose.
2. Tweak (n.) A sharp pinch or jerk; a twist or twitch; as, a tweak of the nose.
3. Tweak (n.) Trouble; distress; tweag.
4. Tweak (n.) A prostitute.